Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.

نویسندگان

  • N M Buchanan
  • E Toubi
  • M A Khamashta
  • F Lima
  • S Kerslake
  • G R Hughes
چکیده

OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome. RESULTS HCQ was not apparently teratogenic. Lupus activity and obstetric outcome in the two groups were similar. CONCLUSION HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.

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عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 55 7  شماره 

صفحات  -

تاریخ انتشار 1996